Rabbit Monoclonal to Histone H3

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简述：Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
应用：WB,IHC/IHF,IF,IP/ChIP
种属反应性：Human,Mouse,Rat

Immunogen	A synthesized peptide derived from human Histone H3.1
Swiss Prot	P68431
Synonyms	Histone H3.1, Histone H3, HIST1H3A;;Histone H3
Observed MW	Calculated MW: 15 kDa ; Observed MW: 17 kDa
Source	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG
Storage/Stability	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
WB	1/1000-1/2000
IP	ChIP:1/20-1/50
IHC	IHC:1/100-1/200;IHF:1/50-1/200
ICC	1/50-1/200

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Western blot analysis of Histone H3 expression in (1) HeLa cell lysate; (2) 3T3 cell lysate.
JLX001 Modulated the Inflammatory Reaction and Oxidative Stress in pMCAO Rats via Inhibiting the TLR2/4-NF-κB Signaling Pathway. -Neurochemical Research
Immunofluorescent analysis of Hela cells, using Histone H3 Antibody.
Immunohistochemical analysis of paraffin-embedded Rat thymus, using the Antibody at 1:200 dilution.