Rabbit Monoclonal Antibody to FAP

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简述：The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用：WB,IHC,IF,IP,ELISA
种属反应性：Human,

Swiss Prot	Q12884
Synonyms	Seprase;170 kDa melanoma membrane-bound gelatinase;Fibroblast activation protein alpha;Integral membrane serine protease;
Source	Rabbit
Clonality	Monoclonal Antibody
Isotype	Rabbit IgG,Kappa
Storage/Stability	-15°C to -25°C/1 year(Do not lower than -25°C)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
WB	1/2000-1/10000
IP	1/50-1/200
IHC	1/200-1/1000
ELISA	1/5000-1/20000
IF/ICC	1/200-1/1000
产品分子量	87kD

MRC-5 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.